DISULFIDE-REDUCED NEOGALACTOSYL SERUM ALBUMIN AND USE OF RADIOLABELED DERIVATIVE THEREOF FOR LIVER IMAGING

摘要

Disclosed are disulfide-reduced neogalactosyl serum albumin and use of its radiolabeled derivative for liver imaging. More particularly, the present invention relates to disulfide-reduced neogalactosyl serum albumin represented by the following Formula 1 and a method of preparing the same, as well as its radiolabeled derivative. Also, the present invention is concerned with a kit for liver imaging, which is capable of radiolabeling neogalactosyl human serum albumin. The radiolabeled compound according to the present invention has excellent stability as well as a high accumulation rate in liver, thereby allowing its application in liver imaging Formula (I), wherein, Ga1, L, A, n, and m are described in detail in the specification.