发明名称 USE OF CARDIOTROPHIN IN HEPATIC DISEASES
摘要 The invention relates to the use of cardiotrophin in hepatic diseases. The invention describes the increased expression of cardiotrophine (CT-1) during the hepatic regeneration process which coincides with the maximum proliferation of hepatocytes. Said invention also relates to the role of CT-1 as a hepatic regeneration stimulator. Moreover, said invention details the hepatoprotective role of CT-1 in different acute hepatic injury models. All of the above reveals the importance of the use of CT-1 in the production of compositions used in the treatment of hepatopathies. The invention relates to said use of CT-1 in different forms and methods, including the recombinant protein and the use of gene sequences that code for CT-1.
申请公布号 WO03027146(A1) 申请公布日期 2003.04.03
申请号 WO2002ES00445 申请日期 2002.09.20
申请人 FUNDACION PARA LA INVESTIGACION MEDICA APLICADA;BUSTOS DE ABAJO, MATILDE;PRIETO VALTUENA, JESUS;LASARTE SAGASTIBELZA, JUAN, JOSE;BAIXERAS LLANO, ELENA 发明人 BUSTOS DE ABAJO, MATILDE;PRIETO VALTUENA, JESUS;LASARTE SAGASTIBELZA, JUAN, JOSE;BAIXERAS LLANO, ELENA
分类号 C12N15/09;A61K35/76;A61K38/00;A61K38/19;A61P1/16;C12N5/06;(IPC1-7):C07K14/52 主分类号 C12N15/09
代理机构 代理人
主权项
地址