| 发明名称 |
SUBSTITUTED AMINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
| 摘要 |
Disclosed are compounds of formula (I) which are useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptid e formation.
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| 申请公布号 |
CA2461603(A1) |
申请公布日期 |
2003.04.03 |
| 申请号 |
CA20022461603 |
申请日期 |
2002.09.24 |
| 申请人 |
ELAN PHARMACEUTICALS, INC. |
发明人 |
GAILUNAS, ANDREA;JOHN, VARGHESE;TUCKER, JOHN ALAN |
| 分类号 |
A61K31/166;A61K31/40;A61K31/4015;A61K31/4045;A61K31/415;A61K31/4184;A61K31/4196;A61K31/4439;A61K31/45;A61K31/4709;A61K31/498;A61K31/538;A61K31/5415;A61P9/00;A61P25/00;A61P25/28;A61P43/00;C07C233/66;C07C233/73;C07D207/26;C07D207/27;C07D207/335;C07D209/08;C07D209/12;C07D209/14;C07D209/42;C07D211/76;C07D231/12;C07D233/22;C07D233/54;C07D233/64;C07D235/12;C07D235/14;C07D249/04;C07D249/08;C07D401/12;C07D403/12;C07D413/04;C07D413/14;C07D417/04;C07D417/14;(IPC1-7):C07D233/54;C07D207/32 |
主分类号 |
A61K31/166 |
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