| 发明名称 |
Substituted bicyclic derivatives useful as anticancer agents |
| 摘要 |
The invention relates to compounds of the formula 1and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals with administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
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| 申请公布号 |
US6541481(B2) |
申请公布日期 |
2003.04.01 |
| 申请号 |
US20010834259 |
申请日期 |
2001.04.12 |
| 申请人 |
PFIZER INC |
发明人 |
KATH JOHN CHARLES;TOM NORMA JACQUELINE;LIU ZHENGYU;COX ERIC DAVID;MORRIS JOEL;BHATTACHARYA SAMIT KUMAR |
| 分类号 |
C07D239/94;A61K;A61K31/165;A61K31/437;A61K31/4706;A61K31/4709;A61K31/4725;A61K31/4741;A61K31/4743;A61K31/4745;A61K31/495;A61K31/505;A61K31/517;A61K31/519;A61K31/5377;A61K31/541;A61P35/00;A61P35/02;A61P43/00;C07D;C07D215/38;C07D239/72;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/12;C07D403/14;C07D405/06;C07D405/14;C07D413/14;C07D417/06;C07D451/06;C07D471/02;C07D471/04;C07D487/00;C07D487/04;C07D491/02;C07D491/048;C07D495/04;C07D498/02;(IPC1-7):A61K31/505 |
主分类号 |
C07D239/94 |
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