An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and methods of use. The peptide or polypeptide may be conjugated to a carrier protein and administered as part of a vaccine or immunogenic composition for prevention or treatment of a disease or disorder.
申请公布号
WO02078607(A3)
申请公布日期
2003.03.27
申请号
WO2002US10155
申请日期
2002.04.02
申请人
THE UNIVERSITY OF MIAMI;LOPEZ, DIANA, M.;HERBERT, LYNN;DORSEY, MANTLEY, JR.;KRAUS, GUNTER;HNATYSZYN, JAMES, H.
发明人
LOPEZ, DIANA, M.;HERBERT, LYNN;DORSEY, MANTLEY, JR.;KRAUS, GUNTER;HNATYSZYN, JAMES, H.