| 发明名称 |
n-Terminal chemisch modifizierte Protein-Zusammensetzungen und Methoden |
| 摘要 |
Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon. <IMAGE> <IMAGE> |
| 申请公布号 |
DE10299044(I1) |
申请公布日期 |
2003.03.27 |
| 申请号 |
DE2002199044C |
申请日期 |
1995.02.08 |
| 申请人 |
AMGEN INC. |
发明人 |
KINSTLER, OLAF, B.;GABRIEL, NANCY, E.;FARRAR, CHRISTINE, E.;DEPRINCE, RANDOLPH, B. |
| 分类号 |
A61K38/21;A61K31/00;A61K38/00;A61K38/19;A61K47/30;A61K47/48;A61P1/16;A61P3/06;A61P7/00;A61P7/06;A61P9/10;A61P25/00;A61P31/12;A61P35/00;A61P37/00;A61P37/04;C07K;C07K1/06;C07K1/107;C07K1/113;C07K1/13;C07K14/52;C07K14/53;C07K14/535;C07K14/555;C07K14/56;C07K17/08;(IPC1-7):C07K14/53 |
主分类号 |
A61K38/21 |
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