| 发明名称 |
Water-insoluble derivatives of hyaluronic acid crosslinked with a biscarbodiimide |
| 摘要 |
This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.
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| 申请公布号 |
US6537979(B1) |
申请公布日期 |
2003.03.25 |
| 申请号 |
US20000540716 |
申请日期 |
2000.03.31 |
| 申请人 |
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;ANIKA THERAPEUTICS, INC. |
发明人 |
KUO JING-WEN;SWANN DAVID A.;PRESTWICH GLENN D. |
| 分类号 |
A61K9/00;A61K47/36;A61K47/48;A61L15/28;A61L27/20;A61L31/04;C08B37/08;(IPC1-7):A61K31/715;A61K9/70 |
主分类号 |
A61K9/00 |
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