摘要 |
PURPOSE: Provided is a method for purifying a 5'-protected thymidine and a derivative thereof. Also, provided is a solvent inclusion compound of a 5'-protected thymidine compound obtained as crystals therefrom. CONSTITUTION: A method for purifying a 5'-protected thymidine comprises the steps of: obtaining a compound represented by formula(1), wherein R¬1 represents optionally substituted trityl; R¬2 represents hydrogen or lower alkyl; and R¬3 represents hydrogen, halogen or substituted hydroxyl, in the form of inclusion crystals including a solvent, in a liquid medium comprising the inclusion solvent; and recovering the inclusion crystals from the liquid medium.
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