发明名称 |
Production of fusion proteins and use for identifying binding molecules |
摘要 |
The invention is directed to methods of producing a fusion protein by administering a nucleic acid encoding the fusion protein to an animal. Following the administration of the nucleic acid to the animal, the protein is produced in vivo and is isolated by removing a biological sample from the animal. These methods allow for the rapid and efficient production and isolation of a protein encoded by any nucleic acid sequence of interest. A fusion protein purified according to these methods can be used to screen for target binding molecules, such as antibodies, that bind to a protein sequence of interest.
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申请公布号 |
US2003049694(A1) |
申请公布日期 |
2003.03.13 |
申请号 |
US20020077213 |
申请日期 |
2002.02.14 |
申请人 |
WU CHUNG-HSIUN;LIN RONG-HWA;HSU PEI-LING |
发明人 |
WU CHUNG-HSIUN;LIN RONG-HWA;HSU PEI-LING |
分类号 |
C12N15/09;C07K14/485;C07K16/00;C07K16/40;C07K19/00;G01N33/68;(IPC1-7):G01N33/00;G01N33/567;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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