发明名称 THERAPEUTIC COMBINATIONS FOR CARDIOVASCULAR AND INFLAMMATORY INDICATIONS
摘要 The present invention provides therapeutic combinations and methods for treating or preventing a hypercholesterolemia-related or an inflammation -related condition in a subject in need of such treatment or prevention. One therapeutic combination comprises an ASBT inhibitor combined with COX-2 inhibitor. A further therapeutic combination comprises an ASBT inhibitor, a COX-2 inhibitor and an HMG Co-A reductase inhibitor. Another therapeutic combination comprises a chromene COX-2 inhibitor and an HMG Co-A reductase inhibitor.
申请公布号 WO02078625(A3) 申请公布日期 2003.03.13
申请号 WO2002US09185 申请日期 2002.03.27
申请人 PHARMACIA CORPORATION;SEIBERT, KAREN;KELLER, BRADLEY, T.;ISAKSON, PETER, C. 发明人 SEIBERT, KAREN;KELLER, BRADLEY, T.;ISAKSON, PETER, C.
分类号 C07D237/14;A61K31/10;A61K31/18;A61K31/19;A61K31/196;A61K31/216;A61K31/22;A61K31/352;A61K31/365;A61K31/366;A61K31/38;A61K31/381;A61K31/382;A61K31/40;A61K31/404;A61K31/405;A61K31/415;A61K31/42;A61K31/421;A61K31/426;A61K31/437;A61K31/44;A61K31/4418;A61K31/4436;A61K31/444;A61K31/47;A61K31/50;A61K31/505;A61K31/535;A61K31/5377;A61K31/554;A61K31/77;A61K45/06;A61P1/04;A61P1/16;A61P1/18;A61P3/06;A61P9/00;A61P9/10;A61P19/06;A61P29/00;C07D207/34;C07D209/24;C07D213/34;C07D213/55;C07D213/61;C07D213/64;C07D213/85;C07D215/12;C07D231/12;C07D239/42;C07D261/08;C07D263/32;C07D265/02;C07D277/10;C07D277/20;C07D277/54;C07D281/10;C07D307/58;C07D309/30;C07D311/22;C07D311/58;C07D311/80;C07D311/92;C07D311/96;C07D333/36;C07D335/06;C07D337/08;C07D401/04;C07D403/06;C07D417/04;C07D471/04;C07D487/08 主分类号 C07D237/14
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