AFFINITY SELECTED SIGNATURE PEPTIDES FOR PROTEIN IDENTIFICATION AND QUANTIFICATION
摘要
A method for protein identification in complex mixtures that utilizes affinity selection of constituent proteolytic peptide fragments unique to a protein analyte. These "signature peptides" function as analytical surrogates. Mass spectrometric analysis of the proteolyzed mixture permits identification of a protein in a complex sample without purifying the protein or obtaining its composite peptide signature.
申请公布号
WO0186306(A3)
申请公布日期
2003.03.13
申请号
WO2001US14418
申请日期
2001.05.04
申请人
PURDUE RESEARCH FOUNDATION;REGNIER, FRED, E.;CHAKRABORTY, ASISH, B.;ZHANG, XIANG