发明名称 Histidine copolymer and methods for using same
摘要 The invention provides a pharmaceutical agent delivery composition comprising: (i) a transport polymer comprising a linear or branched peptide having from about 10 to about 300 amino acid residues, having from about 5 to 100% histidine residues, and optionally having from 0 to about 95% non-histidine amino acid residues; (ii) at least one pharmaceutical agent; and optionally (iii) one or more intracellular delivery components in association with the transport polymer. The invention also provides methods for using such composition to deliver the pharmaceutical agent to the interior of cells.
申请公布号 US2003045465(A1) 申请公布日期 2003.03.06
申请号 US20010018103 申请日期 2001.11.05
申请人 MIXSON A. JAMES 发明人 MIXSON A. JAMES
分类号 A61K9/127;A61K38/08;A61K38/10;A61K38/16;A61K47/48;C07K7/06;C07K7/08;C07K14/00;C12N15/88;(IPC1-7):A61K38/10 主分类号 A61K9/127
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