发明名称 (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE, COMPOSITIONS THEREOF, AND USES AS A DOPAMINE-REUPTAKE INHIBITOR
摘要 The present invention relates to (-)-1-(3,4-dichlorophenyl)-3- azabicyclo[3.1.0]hexane and pharmaceutically acceptable salts thereof, compositions comprising (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and methods for treating or preventing a disorder alleviated by inhibiting dopamine reuptake. In one embodiment, the disorder is attention-deficit disorder, depression, obesity, Parkinson's disease, a tic disorder, or an addictive disorder. The (-)-1-(3, 4- dichlorophenyl)-3-azabicyclo[3.1.0]hexane or pharmaceutically acceptable sal t thereof is preferably substantially free of its corresponding (+)-enantiomer .
申请公布号 CA2458217(A1) 申请公布日期 2003.03.06
申请号 CA20022458217 申请日期 2002.08.14
申请人 DOV PHARMACEUTICAL, INC. 发明人 LIPPA, ARNOLD STAN;EPSTEIN, JOSEPH WILLIAM
分类号 C07D471/08;A61K9/14;A61K31/439;A61K45/00;A61P3/04;A61P25/00;A61P25/16;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P43/00;C07D209/52;(IPC1-7):C07D487/04;A61K31/407 主分类号 C07D471/08
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