发明名称 |
Equine infectious anemia challenge model for testing vaccines, diagnostics and treatments |
摘要 |
The invention relates to a method for infecting equines with an equine infectious anemia virus (EIAV) in order to reproduce a natural infection challenge model. More specifically, the invention provides a multiple low dose equine EIA challenge model comprising administering at least 1 median horse infective dose to an equine using an intravenous route of administration. It is preferable that the EIAV be administered on a repeated basis. The multiple low dose EIA challenge model described herein can be used for testing efficacy of vaccines, treatments and diagnostic tests.
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申请公布号 |
US6528250(B1) |
申请公布日期 |
2003.03.04 |
申请号 |
US20000659030 |
申请日期 |
2000.09.09 |
申请人 |
AKZO NOBEL N.V. |
发明人 |
MONTELARO RONALD;PUFFER BRIDGET;LI FENG;ISSEL CHARLES;HENNESSEY KRISTINA J.;BROWN KAREN K. |
分类号 |
A61P31/14;C07K14/155;C12N7/00;C12N7/04;C12N15/49;(IPC1-7):A61K48/00;A61K39/21;A61K121/00;A61K123/00;C12Q1/70 |
主分类号 |
A61P31/14 |
代理机构 |
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地址 |
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