| 发明名称 |
Glutaryl cephalosporin amidase from Pseudomonas diminuta BS-203 |
| 摘要 |
The invention provides a glutaryl 7-ACA amidase from Pseudomonas diminuta strain BS-203, which catalyzes the hydrolysis of 7-beta-(4-carboxybutanamido)-cephalosporanic acid to 7-aminocephalosporanic acid and glutaric acid. The invention also provides nucleic acid sequences, vectors, and host cells useful in the production of this amidase. The glutaryl 7-ACA amidase can be used for the preparation of 7-aminocephalosporanic acid.
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| 申请公布号 |
US6528300(B2) |
申请公布日期 |
2003.03.04 |
| 申请号 |
US20010957960 |
申请日期 |
2001.09.21 |
| 申请人 |
BRISTOL-MYERS SQUIBB CO. |
发明人 |
BINDER ROSS;BROWN JOANNE L.;FRANCESCHINI THOMAS J.;BURNETT WILLIAM V.;POLITINO MICHAEL;LIU SUO WIN;TONZI SEAN M. |
| 分类号 |
C12N15/09;C07K14/21;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/80;C12N15/31;C12P35/02;C12R1/38;(IPC1-7):C12N9/80;C12N15/00;C12N1/20;C07H21/04 |
主分类号 |
C12N15/09 |
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