| 发明名称 |
PREPARATION OF BETA-MRTHYL CARBAPENEM INTERMEDIATES |
| 摘要 |
<p>The present invention is directed to a process of making a Beta-methyl carbapenem intermediate of formula VI from a compound of formula I <CHEM> wherein R and P' are protecting groups R<1> is a methylmalonic acid ester and Nu is a nucleophilic group. Process intermediates are also disclosed.</p> |
| 申请公布号 |
SI9300486(B) |
申请公布日期 |
2003.02.28 |
| 申请号 |
SI19930000486 |
申请日期 |
1993.09.17 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
CHOI WOO-BAEG;HUMPHREY GUY R.;REIDER PAUL J.;SHINKAI ICHIRO;THOMPSON ANDREW S.;VOLANTE RALPH P. |
| 分类号 |
C07D205/08;C07D295/08;C07D405/04;C07D477/12;(IPC1-7):C07D205/08;C07F7/10;C07F7/08;C07F9/547;A61K31/40;C07D487/04 |
主分类号 |
C07D205/08 |
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