发明名称 METHOD FOR MAKING 4-CARBOXYAMINO-2- SUBSTITUTED -1,2,3,4-TETRAHYDRO-QUINOLINE
摘要 The present inention relates to cholesteryl ester transfer protein (CETP) inhibitors and methods for making the CETP inhibitors. In particular, this invention relates to carboxylic acid ethyl esters of 4-(3,5-bis-trifluoromethylbenzylamino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline and cis-4-amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline, as well as stereoisomers and pharmaceutically acceptable salts thereof, and the methods of preparation thereof.
申请公布号 YU71500(A) 申请公布日期 2003.02.28
申请号 YU2000P000715 申请日期 2000.11.16
申请人 PFIZER PRODUCTS INC. 发明人 DAMON, DAVID BURNS
分类号 A61K;A61K31/16;A61K31/435;A61K31/445;A61K31/47;A61K31/4706;A61P3/06;A61P9/10;C07B61/00;C07C233/08;C07C235/66;C07D;C07D213/12;C07D215/00;C07D215/06;C07D215/20;C07D215/38;C07D215/42;C07D215/44;C07D215/48;C07D215/50;C07D217/00;C07D221/04;C07D311/58;C07D335/06;C07D401/04;C07J 主分类号 A61K
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