摘要 |
The present inention relates to cholesteryl ester transfer protein (CETP) inhibitors and methods for making the CETP inhibitors. In particular, this invention relates to carboxylic acid ethyl esters of 4-(3,5-bis-trifluoromethylbenzylamino)-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline and cis-4-amino-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline, as well as stereoisomers and pharmaceutically acceptable salts thereof, and the methods of preparation thereof. |