发明名称 NEW CRYSTAL MODIFICATION OF TORASEMIDE
摘要 The present invention relates to the characterization of a new crystal modification III of torasemide, to a process for the preparation thereof by the use of controlled acidifying of alkaline solutions of torasemide with inorganic or organic acids with or without addition of a crystal seed, to its use as a raw material for the preparation of the crystal modification I of torasemide and of pharmaceutically acceptable salts of torasemide as well as to pharmaceutical forms containing this new crystal modification III of torasemide.
申请公布号 YU24001(A) 申请公布日期 2003.02.28
申请号 YU20010000240 申请日期 1999.10.01
申请人 PLIVA D.O. 发明人 FILIC, DARKO;DUMIC, MILJENKO;DANILOVSKI, ALEKSANDAR;KLEPIC, BOZENA;FISTRIC, INES;ORESIC, MARINA;HORVAT, MIKULCIC JASNA
分类号 A61K9/20;A61K31/44;A61K31/4409;A61P7/02;A61P9/10;A61P9/12;A61P11/06;A61P27/06;A61P35/00;C07D213/53;C07D213/71;C07D213/74 主分类号 A61K9/20
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