发明名称 Phenoxypropanolamines, method for producing them and pharmaceutical compositions containning them
摘要 The invention relates to compounds of formula (I) where R1 represents a hydrogen or halogen atom or an -S(O)z-(C1-C4)alkyl, -S(O)z-(C1-C4)R3, -SO2-NH-(C1-C4)alkyl, -NHCO(C1-C4) alkyl, -CO(C1-C4)alkyl or -NHSO2-(C1-C4)alkyl group; m and n independently represent 0, 1 or 2; A represents a group of formula (a) or (b): where X is N or CH; R2 represents an -SO2-R3, -CO-R3 or -CO-(C1-C4)-alkyl group; R3 represents a phenyl group, optionally substituted by a (C1-C4)alkyl or (C1-C4)alkoxy group, one or two halogen atoms or a heterocycle; R4 represents a hydrogen or halogen atom or a (C1-C6)alkyl, (C1-C4)alkoxy, -COOH, -COO(C1-C4)alkyl, -CN, -CONR5R6, -NO2, -NHSO2(C1-C4)alkyl or -SO2NR5R6 group; z is 1 or 2; R5 and R6 independently represent a hydrogen atom or a (C1-C4)alkyl, phenyl or phenyl (C1-C4)alkyl group; and their salts or solvates, to a process for their preparation, to synthetic intermediates and to the pharmaceutical compositions comprising them.
申请公布号 US2003040530(A1) 申请公布日期 2003.02.27
申请号 US20020149497 申请日期 2002.06.12
申请人 CECCHI ROBERTO 发明人 CECCHI ROBERTO
分类号 C07D211/26;A61K31/4468;A61K31/451;A61K31/4545;A61P1/00;A61P3/00;A61P3/04;A61P3/10;A61P15/06;A61P25/00;A61P25/24;A61P27/06;C07D211/58;C07D401/04;(IPC1-7):A61K31/454;A61K31/445;C0741/02;C07D211/68 主分类号 C07D211/26
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