发明名称 |
TOPICAL COMPOSITION FOR FOLLICULAR DELIVERY OF AN ORNITHINE DECARBOXYLASE INHIBITOR |
摘要 |
Polyethylene glycol ethers of alkyl alcohols having the general formula CH3(CH2)xCH2(OCH2CH2)nOH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are preferred), poloxamer 185, poloxamer 407, N,N-dimethyl dodecylamine N-oxide, and mixtures thereof, are employed to increase follicular delivery and/or follicular residence time of certain water soluble ornithine decarboxylase inhibitors of which 2(difluoromethyl)-2,5-diamino pentanoic acid and its pharmaceutically acceptable salts, hydrates, optical enantiomers and racemic mixture are preferred.
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申请公布号 |
WO03015729(A1) |
申请公布日期 |
2003.02.27 |
申请号 |
WO2002US25754 |
申请日期 |
2002.08.13 |
申请人 |
WOMEN FIRST HEALTHCARE, INC. |
发明人 |
CHOU, JOYCE, T.;PARAB, PRAKASH |
分类号 |
A61K9/06;A61K8/00;A61K8/02;A61K8/06;A61K8/30;A61K8/36;A61K8/39;A61K8/40;A61K8/41;A61K8/43;A61K8/44;A61K8/49;A61K8/60;A61K8/64;A61K8/66;A61K8/72;A61K8/86;A61K9/00;A61K9/08;A61K9/107;A61K9/12;A61K9/20;A61K9/70;A61K31/13;A61K31/132;A61K31/155;A61K31/198;A61K31/7076;A61K47/10;A61K47/18;A61K47/34;A61P17/14;A61P43/00;A61Q5/00;A61Q5/02;A61Q7/00;A61Q7/02;(IPC1-7):A61K7/06 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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