A diagnostic test for preclinical and clinical Alzheimer's disease is based on plasma levels of A.beta.40, A.beta.42, their ratio, or their rate of entry following administration of antibodies that sequester A.beta.. Alterations o f any of these parameters from control values identifies preclinical or clinic al Alzheimer's disease.
申请公布号
CA2457145(A1)
申请公布日期
2003.02.27
申请号
CA20022457145
申请日期
2002.08.16
申请人
WASHINGTON UNIVERSITY;ELI LILY AND COMPANY
发明人
BALES, KELLY R.;CUMMINS, DAVID J.;PAUL, STEVEN M.;HOLTZMAN, DAVID M.;DEMATTOS, RONALD;VASQUEZ, MAXIMILIANO J.;JIA, AUDREY YUNHUA;TSURUSHITA, NAOYA