The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a target GPCR gene. Such transgenic mice are useful as models for desease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
申请公布号
WO0203789(A3)
申请公布日期
2003.02.27
申请号
WO2001US21498
申请日期
2001.07.06
申请人
DELTAGEN, INC.;ALLEN, KEITH, D.;BRENNAN, THOMAS, J.