发明名称 Antisense inhibition of PKA regulatory subunit RII alpha expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of PKA regulatory subunit RII alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PKA regulatory subunit RII alpha. Methods of using these compounds for modulation of PKA regulatory subunit RII alpha expression and for treatment of diseases associated with expression of PKA regulatory subunit RII alpha are provided.
申请公布号 US6524854(B1) 申请公布日期 2003.02.25
申请号 US20010954560 申请日期 2001.09.11
申请人 ISIS PHARMACEUTICALS, INC. 发明人 MONIA BRETT P.;COWSERT LEX M.
分类号 A61K38/00;C12N15/113;(IPC1-7):C12N15/85;C12N15/86;C07H21/04;C07H21/02;C12Q1/68 主分类号 A61K38/00
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