FAT ACCUMULATION-MODULATING COMPOUNDS

摘要

The present invention pertains to compounds effective at modulating fatty acid or triglyceride accumulation by fat cells, such compounds having therapeutic potential as regulators of body mass and for the treatment of overweight individuals, obesity, and metabolic disorders. Featured compounds are those having the structure set forth and exemplified herein: Formula (I) wherein Ar is a substituted or unsubstituted phenyl group; R is a hydrogen or C1-6 alkyl group; and P is a substituted or unsubstituted nitrogen-containing heteroaryl group; said compound having the property of modulating the accumulation of fatty acids by cells. Therapeutic methods and pharmaceutical compositions featuring these compounds are also provided.