发明名称 |
PROCESS FOR THE FERMENTATIVE PREPARATION OF L-AMINO ACIDS USING CORYNEFORM BACTERIA |
摘要 |
The invention relates to a process for the preparation of L-amino acids, in which the following steps are carried out: a) fermentation of the coryneform bacteria which produce the desired L-amino acid and in which at least the gene which codes for trehalose phosphatase and/or the gene which codes for maltooligosyl-trehalose synthase and/or the gene which codes for maltooligosyl-trehalose trehalohydrolase is or are attenuated, b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and c) isolation of the L-amino acid,and optionally bacteria in which further genes of the biosynthesis pathway of the desired L-amino acid are addtionally enhanced are employed, or bacteria in which the metabolic pathways which reduce the formation of the desired L-amino acid are at least partly eliminated are employed. |
申请公布号 |
WO03014370(A2) |
申请公布日期 |
2003.02.20 |
申请号 |
WO2002EP05264 |
申请日期 |
2002.05.14 |
申请人 |
DEGUSSA AG |
发明人 |
WOLF, ANDREAS;SCHISCHKA, NATALIE;HERMANN, THOMAS;MORBACH, SUSANNE;KRAEMER, REINHARD |
分类号 |
C12N1/21;C12N9/10;C12N9/90;C12P13/08;C12P13/14 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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