摘要 |
The present invention describes novel methods, assays and kits for identifying and / or quantifying Aminoglycoside Binding Molecules (ABMs), enzymes modifying such molecules, and compounds modulating the interaction between ABMs and either enzymes or aminoglycosides, by exploiting the scintillation proximity effect. The invention, which makes use of aminoglycoside-coated scintillating supports, can be adapted to high throughput screening formats. |
申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;CAMPS, MONTSERRAT;CHABERT, CHRISTIAN;PERRIN, DOMINIQUE;MARTIN, THIERRY;WYMANN, MATTHIAS, PAUL;ROMMEL, CHRISTIAN |
发明人 |
CAMPS, MONTSERRAT;CHABERT, CHRISTIAN;PERRIN, DOMINIQUE;MARTIN, THIERRY;WYMANN, MATTHIAS, PAUL;ROMMEL, CHRISTIAN |