发明名称 NOVEL 2,4-DIAMINOTHIAZOLE DERIVATIVES
摘要 Novel 2,4-diaminothiazole derivatives of the general formula (I) which inhib it GSK-3 (glycogen synthase kinase-3), use of these compounds as medicaments, pharmaceutical compositions comprising the compounds and methods of treatmen t employing these compounds and compositions. The present compounds may be useful for the treatment of disorders, syndromes, diseases and conditions, wherein an inhibition of GSK-3 (glycogen synthase kinase-3) is beneficial, especially IGT (impaired glucose tolerance), type 1 diabetes, type 2 diabete s, obesity, Alzheimer's disease and bipolar disorder.
申请公布号 CA2455753(A1) 申请公布日期 2003.02.13
申请号 CA20022455753 申请日期 2002.07.22
申请人 NOVO NORDISK A/S 发明人 HANSEN, BO FALCK;BOWLER, ANDREW NEIL
分类号 C07D277/20;A61K31/426;A61K31/427;A61K31/454;A61K31/496;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P25/18;A61P25/28;A61P43/00;C07D277/42;C07D417/06;C07D417/12;C07D417/14;(IPC1-7):C07D277/42;A61K31/443 主分类号 C07D277/20
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