| 摘要 |
A pre-filled syringe assembly is achieved which prevents, with a strong force, a stopper provided therein from being pulled out, and wherein the stopper can be prevented from being scratched. The pre-filled syringe assembly includes a barrel and a flanged fixing member which is screwed to the barrel, wherein a stopper-pull-out prevention portion is provided by the flanged fixing member. It is desirable for a reuse-prevention projection and a notch to be provided on one and the other of the flanged fixing member and the plunger, which engage with each other when the plunger is inserted into the barrel up to a position therein whereby a liquid drug in the barrel is totally discharged. An air evacuation groove can be provided on the inner peripheral surface of the barrel, which is defined by a gap between the barrel and the stopper when the stopper is positioned at the open end side of the barrel.
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