摘要 |
<p>A substance comprising a substance recognizing PD-1, a substance recognizing a membrane-protein occurring in the cell membrane wherein PD-1 is expressed, and a linker. The substance specific to PD-1 can selectively recognize PD-1 and the membrane-protein occurring in the cell membrane wherein PD-1 is expressed and transfer a PD-1 suppressive signal. Thus, it is useful in treating and/or preventing diseases caused by immunopathy.</p> |