发明名称 2-aryl indole derivative as antagonists of tachykinins
摘要 The present invention relates to compounds of the formula (I):wherein R1a, R1b, R2, R3, R4, R5, X and n are defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis and postherpetic neuralgia.
申请公布号 US6518273(B1) 申请公布日期 2003.02.11
申请号 US20010914893 申请日期 2001.09.04
申请人 MERCK SHARP & DOHME LTD. 发明人 CHAPMAN KEVIN TYLER;DINNELL KEVIN;ELLIOTT JASON MATTHEW;HOLLINGWORTH GREGORY JOHN;HUTCHINS STEVEN MICHAEL;SHAW DUNCAN EDWARD;WILLOUGHBY CHRISTOPHER ALAN
分类号 A61P25/24;C07D209/18;C07D401/12;C07D403/06;C07D403/12;C07D405/12;C07D487/08;(IPC1-7):A61K31/496 主分类号 A61P25/24
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