发明名称 |
Anionic polymers as toxin binders and antibacterial agents |
摘要 |
The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.
|
申请公布号 |
US6517826(B1) |
申请公布日期 |
2003.02.11 |
申请号 |
US20000723596 |
申请日期 |
2000.11.28 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
KURTZ CAROLINE ISABELLE BACON;FITZPATRICK RICHARD |
分类号 |
A61K31/78;A61K31/00;A61K31/74;A61K31/795;A61K38/14;A61P1/00;A61P31/00;A61P31/04;C08F20/06;C08F20/54;C08K5/00;C08L25/18;(IPC1-7):A61K31/74;A61K39/40 |
主分类号 |
A61K31/78 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|