| 摘要 |
Compositions and methods are provided which are useful in determining the le vels of the C-telopeptide of human Type I collagen. The levels of the C-telopeptide are used as a marker of collagen degradation in an individual, and thus serve as a sensitive and spe cific indicator of bone resorption. Assays for the C-telopeptide find a variety of uses, including use in diagnosing metabolic bone disord ers such as osteoporosis or postmenopausal rapid bone losers, monitoring the eff icacy of therapeutic regimens designed to treat such dis orders, determining the extent of imbalances between bone formation and resorption.< /SDOAB>
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