发明名称 COMPOSITIONS AND METHODS USED FOR DECREASING OCULAR HYPERTENSION
摘要 FIELD: medicine, ophthalmology. SUBSTANCE: three variants of improved ophthalmological composition are described which are especially useful for decreasing glaucoma- associated intraocular pressure. Compositions contain active substance out of prostaglandins' class, for example, isopropyl ether 13,14,dihydro-15-keto-20-ethyl-PGF2alpha, in combination with certain nonionogenic surface-active substances, conservants and nonionic tonicity-regulating agents. New modified compositions based upon prostaglandins are manufactured by a simple method and possess balanced efficiencies in decreasing intraocular pressure and conservation, tolerance for an eye and storage duration. EFFECT: higher efficiency. 23 cl, 14 ex, 3 tbl
申请公布号 RU2197970(C2) 申请公布日期 2003.02.10
申请号 RU19990121641 申请日期 1998.03.13
申请人 NOVARTIS AG 发明人 RID KENNET UORREN;JUN' SHAOFEHN;SOU MEHRI;PIKOK REDZHAJNA FLINN
分类号 A61K9/08;A61B5/103;A61B5/11;A61K9/00;A61K31/557;A61K31/5575;A61K47/00;A61P27/02;A61P27/06;(IPC1-7):A61K31/557 主分类号 A61K9/08
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