| 摘要 |
A medicament for inhibiting sodium/calcium exchange system which comprises a s an active ingredient a substance selected from the group consisting of an aminobenzenesulfonic acid derivative represented by the following general formula (I) and a salt thereof, and a hydrate thereof and a solvate thereof: wherein R1 represents a hydrogen atom, a C1-C6 alkyl group and the like; R2 represents a hydrogen atom, a C1-C6 alkyl group, or a C7-C12 aralkyl group; and n represents an integer of from 1 to 4. The medicament is useful for suppression of intracellular calcium accumulation generated under very sever e dyscrasic condition as a result of clinically-occurred combination of ischemia/reperfusion and intracellular sodium increase.
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