| 发明名称 |
ASSAYS FOR IDENTIFYING MODULATORS OF RHOMBOID POLYPEPTIDES |
| 摘要 |
The present invention relates to proteins of the conserved Rhomboid family, which are involved in various signalling pathways within cells. Rhomboid proteins are found to possess a novel serine protease activity which cleaves within the transmembrane domain of a polypeptide substrate. Methods and uses of this activity are provided. |
| 申请公布号 |
WO02093177(A3) |
申请公布日期 |
2003.02.06 |
| 申请号 |
WO2002GB02234 |
申请日期 |
2002.05.13 |
| 申请人 |
MEDICAL RESEARCH COUNCIL;FREEMAN, MATTHEW |
发明人 |
FREEMAN, MATTHEW |
| 分类号 |
G01N33/50;A61K38/00;A61P9/10;A61P17/02;A61P17/06;A61P25/02;A61P31/04;A61P35/00;C07K14/435;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/50;C12N9/64;C12N15/09;C12Q1/37;G01N33/15;G01N33/68 |
主分类号 |
G01N33/50 |
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