| 发明名称 |
PROCESS FOR THE PREPARATION OF 2'-3'-DIDEOXY-2',3'-DIDEHYDRO-NUCLEOSIDES |
| 摘要 |
The present invention is an efficient synthetic route to 2',3'-dideoxy-2'3'-didehydro-nucleosides. This process utilizes metal mediated allyl chemistry to achieve coupling of a heterocyclic base, including a purine, pyrimidine, or other heterocylic or heteroaryl compound to a glycal to produce a nucleoside with high regio- and enantioselectivity.
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| 申请公布号 |
WO03010179(A1) |
申请公布日期 |
2003.02.06 |
| 申请号 |
WO2001US23267 |
申请日期 |
2001.07.24 |
| 申请人 |
EMORY UNIVERSITY;LIOTTA, DENNIS, C.;CHOI, WOO-BAEG |
发明人 |
LIOTTA, DENNIS, C.;CHOI, WOO-BAEG |
| 分类号 |
A61P31/18;C07D307/32;C07D405/04;C07H19/06;C07H19/16;(IPC1-7):C07H19/06;A61K31/705 |
主分类号 |
A61P31/18 |
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