发明名称 |
CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN |
摘要 |
This invention is directed to a method for preventing or treating neuropathi c pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amoun t of a compound of Formula (I): Formula (I) wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected fr om the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
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申请公布号 |
CA2454049(A1) |
申请公布日期 |
2003.01.30 |
申请号 |
CA20022454049 |
申请日期 |
2002.07.11 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
ZHAO, BOYU;PLATA-SALAMAN, CARLOS R.;CODD, ELLEN C. |
分类号 |
A61P25/02;A61K31/27;A61P25/04;A61P25/06;(IPC1-7):A61K31/27 |
主分类号 |
A61P25/02 |
代理机构 |
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地址 |
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