发明名称 CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEUROPATHIC PAIN AND CLUSTER AND MIGRAINE HEADACHE-ASSOCIATED PAIN
摘要 This invention is directed to a method for preventing or treating neuropathi c pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a therapeutically effective amoun t of a compound of Formula (I): Formula (I) wherein phenyl is substituted at X with one to five halogen atoms independently selected from the group consisting of fluorine, chlorine, bromine and iodine; and; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-C4 alkyl; wherein C1-C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected fr om the group consisting of hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, amino, nitro and cyano).
申请公布号 CA2454049(A1) 申请公布日期 2003.01.30
申请号 CA20022454049 申请日期 2002.07.11
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC. 发明人 ZHAO, BOYU;PLATA-SALAMAN, CARLOS R.;CODD, ELLEN C.
分类号 A61P25/02;A61K31/27;A61P25/04;A61P25/06;(IPC1-7):A61K31/27 主分类号 A61P25/02
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