An antimalarial agent which is effective against malaria plasmodium having resistance to various antimalarial agents and is reduced in side effects. The antimalarial agent contains as the active ingredient a rhodacyanine dye compound represented by the general formula (I) (wherein R<sp>1</sp> and R<sp>2</sp> each independently represents hydrogen, (un)substituted C<sb>1−8</sb> alkyl, or C<sb>6−8</sb> aryl or R<sp>1</sp> and R<sp>2</sp> are bonded to each other to form an (un)substituted six−membered ring; B represents a conjugated system; n is 0, 1, or 2; A represents a group of atoms necessary for forming a five− or six−membered heterocycle, which may be unsubstituted or have two or more substituents, which may be bonded to each other; and Q represents a pharmaceutically acceptable anion). (Chemical formula (1))
申请公布号
WO03007948(A1)
申请公布日期
2003.01.30
申请号
WO2002JP07255
申请日期
2002.07.17
申请人
JAPAN SCIENCE AND TECHNOLOGY CORPORATION;IHARA, MASATAKA;TAKASU, KIYOSEI;INOUE, HIROSHI;WATAYA, YUSUKE;KIM, HYE-SOOK