发明名称 |
ACTIVATORS OF CYCLIN-DEPENDENT KINASES |
摘要 |
A new gene family involved in cell cycle regulation was discovered. This family has been termed activators of cyclin-dependent kinases (ACDKs). A number of ACDK genes have been cloned and sequenced. Proteins encoded by ACDK genes specifically were shown to interact with CDKs and pRb, and to upregulate the kinase activity of a CDK using pRb as a substrate. Progression of a cell through the cell cycle can be regulated by modulating ACDK expression in the cell. |
申请公布号 |
WO03008557(A2) |
申请公布日期 |
2003.01.30 |
申请号 |
WO2002US23147 |
申请日期 |
2002.07.19 |
申请人 |
UNIVERSITY OF FLORIDA |
发明人 |
SHE, JIN-XIONG;WANG, CONG-YI;KUMAR, PRADEEP, G. |
分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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