METHODS FOR REGULATION OF IMMUNE RESPONSES TO CONDITIONS INVOLVING MEDIATOR-INDUCED PATHOLOGY

摘要

The present invention relates to methods for inhibiting the release and/or biological activity of the cytokine macrophage migration inhibitory factor (MIF). In particular, the invention relates to the uses of such methods for the treatment of various conditions involving mediator-induced diseases or pathology, which include, but are not limited to sepsis, severe sepsis, septic shock, inflammation, graft versus host disease, and/or autoimmune diseases.