发明名称 Thiazolidinedione derivative and its use as antidiabetic
摘要 <p>A polymorphic form of 5-Ä4-Ä2-(N-methyl-N-(2-pyridyl)amino)ethoxyÜbenzylÜthiazolidine-2,4-di one, maleic acid salt (the "Polymorph") characterised in that it provides: (i) an infra red spectrum containing peaks at 1752, 1546, 1154, 621, and 602 cm&lt;-1&gt;; and/or (ii) a Raman spectrum containing peaks at 1751, 1243 and 602 cm&lt;-1&gt;; and/or (iii) a solid-state nuclear magnetic resonance spectrum containing peaks at 111.9, 114.8, 119.6, 129.2, 134.0, 138.0, 144.7, 153.2, 157.1, 170.7, 172.0 and 175.0 ppm; and/or (iv) an X-ray powder diffraction (XRPD) pattern which gives calculated lattice spacings of 6.46, 5.39, 4.83, 4.68, 3.71, 3.63, 3.58, and 3.48 Angstroms.; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compund in medicine.</p>
申请公布号 EP1277753(A1) 申请公布日期 2003.01.22
申请号 EP20020080319 申请日期 2000.04.19
申请人 SMITHKLINE BEECHAM PLC 发明人 BLACKLER, PAUL DAVID JAMES;GILES, ROBERT GORDON;MOORE, STEPHEN;SASSE, MICHAEL,JOHN
分类号 A61K31/4439;A61P3/10;C07D417/00;C07D417/12;(IPC1-7):C07D417/12;A61K31/427 主分类号 A61K31/4439
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