Monoclonal antibody specific to polypeptide which induces interferon-Ggamma production

摘要

A monoclonal antibody which is specific to a polypeptide having a molecular weight of 18,500 3,000 daltons on SDS-PAGE and a pI of 4.9 1.0 on chromatofocusing. The monoclonal antibody is obtainable from hybridomas and can be used for the purification and detection of the polypeptide. The polypeptide strongly induces the IFN-gamma production by immunocompetent cells with only a small amount, and dose not cause serious side effects even when administered to human in a relatively-high dose