A method of determining chromatin structure is described. The method comprises the steps of (i) fragmenting a nucleotide sequence at multiple HSs; and (ii) analysing fragments formed in step (i) from a plurality of sequences. In a preferred aspect, the present invention provides a method of determining chromatin structure in a nucleic acid sample comprising the steps of (i) treating the sample to fragment the nucleic acid therein at multiple HSs; and (ii) analysing fragments formed in step (i) from a plurality of genes.
申请公布号
WO03004702(A2)
申请公布日期
2003.01.16
申请号
WO2002GB03080
申请日期
2002.07.04
申请人
IMPERIAL COLLEGE INNOVATIONS LIMITED;WEINZIERL, ROBERT, OTTO, JOHANNES