发明名称 |
GENETIC ANALYSIS OF PEYERS'S PATCHES AND M CELLS AND METHODSAND COMPOSITIONS TARGETING PEYER'S PATCHES AND M CELL RECEPTORS |
摘要 |
Methods of increasing of or decreasing the levels of a protein in a PP cell; methods of increasing antigen, vaccine, DNA vaccine delivery to M cells, use of human serum albumin and other transport enhancing proteins to enhance ora l drug delivery; use of calreticulin to enhance oral antigen delivery, use of other cell surface proteins, receptors, and transporters to enhance delivery to M cells of antigens or vaccine delivery vehicles, use of other cytoplasmi c proteins to regulate intracellular trafficking and delivery to mucosal immun e sampling and processing systems.
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申请公布号 |
CA2443644(A1) |
申请公布日期 |
2003.01.16 |
申请号 |
CA20022443644 |
申请日期 |
2002.04.04 |
申请人 |
ELAN CORPORATION PLC |
发明人 |
BYRNE, DARAGH;BRAYDEN, DAVID;O'MAHONY, DANIEL J.;HIGGINS, LISA;LAMBKIN, IMELDA |
分类号 |
A61K38/00;C07K7/06;C07K7/08;C07K14/00;C07K14/47;C12N15/12;(IPC1-7):C12N15/12;A61K39/00;A61K48/00;A61K47/42;A61K47/48;C12N15/63 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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