发明名称 |
Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof |
摘要 |
The present invention relates to production of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid useful as an intermediate for pharmaceutical products, by an industrial means, economically, safely in a good yield. Novel 2-(2'-cyclohexen-1'-yl)-2-hydroxy-2-phenylacetic acid ester obtained by reacting cyclohexene and benzoylformic acid ester in the presence of a Lewis acid is hydrolyzed and reduced to give 2-cyclohexyl-2-hydroxy-2-phenylacetic acid.
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申请公布号 |
US2003013911(A1) |
申请公布日期 |
2003.01.16 |
申请号 |
US20010992167 |
申请日期 |
2001.11.06 |
申请人 |
SUMIKA FINE CHEMICALS CO., LTD. |
发明人 |
IKEMOTO TETSUYA;GAO WEI-GUO;TAKEDA MITSUHIRO;IGI MASAMI |
分类号 |
C07C51/09;C07C51/36;C07C67/303;C07C67/343;C07C69/732;(IPC1-7):C07C59/54 |
主分类号 |
C07C51/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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