A liposome composition having resistance to freeze/thaw damage.

摘要

A liposome composition having improved protection from freeze/thaw damage is described. The liposome composition contains an osmotic gradient across the liposome lipid bilayer, wherein the osmolarity of the external medium is higher than the osmolarity of the liposome inner medium. Typically, the external medium includes a salt and a cryoprotectant to achieve the increase observed in osmolarity.