METHODS FOR INDUCING AN IMMUNE RESPONSE WITH AN ELEVATED TH1/TH2 RATIO, BY INTRACELLULAR INDUCTION OF NFKAPPAB

摘要

The present invention provides a method of increasing the TH1:TH2 ratio of an immune response, comprising the step of supplying to an antigen presenting cell (APC) such as a dendritic cell (DC) or precursor cell, an intracellular activator of A-PC, such as DC, function. The invention also provides a method of treating a patient with or at risk of allergy comprising the step of supplying an intracellular activator of A-PC, such as DC, function, or an intracellular inducer of NF kappa B, to the patient or to an APC, such as a DC, or precursor cell, of the patient.