发明名称 |
Attenuated HIV strains and use thereof |
摘要 |
The present invention provides an isolated human immunodeficiency virus, and methods for obtaining the same, comprising at least one non-revertant mutation capable of delaying or diminishing the pathological behavior of said human immunodeficiency virus in comparison with a human immunodeficiency virus not having at least one such mutation. The invention further provides a vaccine against acquired immunodeficiency syndrome comprising the isolated human immunodeficiency virus according to the invention. Said virus can also be used for diagnostic assays in HIV-infected patients.
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申请公布号 |
US2003008275(A1) |
申请公布日期 |
2003.01.09 |
申请号 |
US20010948977 |
申请日期 |
2001.09.07 |
申请人 |
GOUDSMIT JAAP;CORNELISSEN MARION |
发明人 |
GOUDSMIT JAAP;CORNELISSEN MARION |
分类号 |
C07K14/16;C12N7/01;C12N7/04;(IPC1-7):C12Q1/70;A61K39/21;A61K38/04;C07H21/04;C12Q1/68;C12N7/00;C07K5/00;C07K7/00;C07K16/00;C07K17/00 |
主分类号 |
C07K14/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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