METHOD OF CONSTRUCTING JOINT DISEASE MODEL ANIMAL

摘要

A method of constructing a model nonhuman mammal of meniscetomy as a model animal of a joint disease such as arthritis deformans characterized by comprising cutting the tibial collateral ligament, anterior cruciate ligament and posterior cruciate ligament of a nonhuman mammal (in particular, a rat), and then further cutting its inner meniscens of the same leg to thereby substantially induce arthritis mutilans.