CELL MEMBRANE-DIRECTED DRUGS

摘要

Drugs wherein peptides having an affinity specific to phospholipids, preferably those which constitute a lipid bilayer forming a cell cortex and the content of which in the lipid bilayer increases in abnormal cells, for example, injured, denatured or activated cells are bonded to physiologically active substances; deoxyribonucleic acids (DNA) encoding the amino acid sequences of the drugs when the physiologically active substances are peptides; and processes for producing these drugs. These drugs and novel peptides are useful as preventives and remedies for diseases accompanied by blood coagulation disorders, inflammation and immune responses.